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EP 1 218 747 A1

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(43) Date of publication: 03.07.2002 Bulletin 2002/27 (21) Application number: 00969290.6 (22) Date of filing: 25.09.2000

(51) International Patent Classification (IPC)7: G01N 33/573, G01N 33/68, C12N 9/12, C07K 14/47, C12Q 1/48 (86) International application number: PCT/EP0009/326 (87) International publication number: WO 0122/090 (29.03.2001 Gazette 2001/13)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 24.09.1999 EP 99118847 (71) Applicant: Boehringer Ingelheim International GmbH 55216 Ingelheim (DE)	(72) Inventors: DAVID, Jean-Pierre A-1020 Wien (AT) SABAPATHY, Kanaga Singapore 600406 (SG) BEHRENS, Axel CH-8032 Zürich (CH) WAGNER, Erwin, F. A-1030 Vienna (AT) (74) Representative: Laudien, Dieter, Dr. et al c/o Boehringer Ingelheim GmbH 55216 Ingelheim 55216 Ingelheim (DE)