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(11)

EP 1 220 872 A1

(12)

(43) Date of publication: 10.07.2002 Bulletin 2002/28 (21) Application number: 00966698.3 (22) Date of filing: 04.10.2000

(51) International Patent Classification (IPC)7: C07K 7/08, A61K 38/10, A61P 35/00 (86) International application number: PCT/US0021/998 (87) International publication number: WO 0125/266 (12.04.2001 Gazette 2001/15)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 06.10.1999 US 157950 P (71) Applicant: Pharmacia Corporation Chicago, IL 60680-5110 (US)	(72) Inventors: SHAILUBHAI, Kunwar Chesterfield, MO 63017 (US) CURRIE, Mark, G. St. Charles, MO 63304 (US) (74) Representative: Beil, Hans Christoph, Dr.  Hansmann & Vogeser,Patent- und Rechtsanwälte,Postfach 80 01 40 65901 Frankfurt 65901 Frankfurt (DE)