(19)
(11)
EP 1 220 928 A2
(12)
(88)
Date of publication A3:
17.01.2002
(43)
Date of publication:
10.07.2002
Bulletin 2002/28
(21)
Application number:
00967217.1
(22)
Date of filing:
02.10.2000
(51)
International Patent Classification (IPC)
7
:
C12N
15/54
,
C12N
15/90
,
C12N
15/63
,
C12N
15/67
,
C12N
15/85
,
C12N
9/10
,
C12N
5/10
,
C12N
1/21
,
A01K
67/027
(86)
International application number:
PCT/US0027/065
(87)
International publication number:
WO 0123/541
(
05.04.2001
Gazette 2001/14)
(84)
Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI
(30)
Priority:
30.09.1999
US 156953 P
(71)
Applicant:
ALEXION PHARMACEUTICALS, INC.
New Haven, CT 06511 (US)
(72)
Inventors:
FODOR, William, L.
Madison, CT 06443 (US)
RAMSOONDAR, Jagdeece, J.
Hamilton, NY 13346 (US)
(74)
Representative:
Maschio, Antonio
D Young & Co,21 New Fetter Lane
London EC4A 1DA
London EC4A 1DA (GB)
(54)
COMPOSITIONS AND METHODS FOR ALTERING GENE EXPRESSION