(19)

(11)

EP 1 221 941 A1

(12)

(43) Date of publication: 17.07.2002 Bulletin 2002/29 (21) Application number: 00982684.3 (22) Date of filing: 18.10.2000

(51) International Patent Classification (IPC)7: A61K 9/14, A61K 9/16, A61K 9/19, A61K 9/20, A61K 9/46 (86) International application number: PCT/US0041/225 (87) International publication number: WO 0128/523 (26.04.2001 Gazette 2001/17)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 20.10.1999 US 421905 (71) Applicant: WM. WRIGLEY JR. COMPANY ChicagoIllinois 60611 (US)	(72) Inventors: REAM, Ronald, L. Plano, IL 60545 (US) WOKAS, William, J. Bolingbrook, IL 60440 (US) (74) Representative: Rickard, David John  IPULSE,26 Mallinson Road London SW11 1BP London SW11 1BP (GB)