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(11)

EP 1 222 158 A1

(12)

(43) Date of publication: 17.07.2002 Bulletin 2002/29 (21) Application number: 00970985.8 (22) Date of filing: 18.10.2000

(51) International Patent Classification (IPC)7: C07C 69/753, A61K 31/215, C11D 7/54 (86) International application number: PCT/US0028/795 (87) International publication number: WO 0128/973 (26.04.2001 Gazette 2001/17)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.10.1999 EP 99870218 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)

(72) Inventors: CHIARADONNA, Giuseppe,Universita di Pisa I-56126 Pisa (IT) CICOGNA, Francesca,Universita di Pisa I-56126 Pisa (IT) INGROSSO, Giovanni,Universita di Pisa I-56126 Pisa (IT) PINZINO, Calogero,Molecolare, CNR, Pisa I-56126 Pisa (IT) DEL DUCA, Valerio I-80064 Massalubrense (IT) SCIALLA, Stefano I-00128 Rome (IT) FRANCHI, Emanuela,Universita di Pisa I-56126 Pisa (IT) (74) Representative: Goodier, Claire et al Procter & Gamble Services Company NV,Temselaan 100 1853 Strombeek-Bever 1853 Strombeek-Bever (BE)