ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFI....CY................................*JDIM360 Ver 2.15 (14 Jul 2008) - 2999001/01222192CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120081001W173deBibliographieenBibliographyfrBibliographieEP00966144.8200010062002050620061115enenen157850 P19991006US2008100120084020020717200229200806182008252008022520081001200840C07D 493/04 20060101AFI20010417BHEP A61K 31/34 20060101ALI20010417BHEP A61K 31/36 20060101ALI20010417BHEP A61P 31/12 20060101ALI20010417BHEP deHEXAHYDROFURO¬2,3-B FURAN-3-YL-N- 3-¬(1,3-BENZODIOXOL-5-YLSULFONYL)(ISOBUTYL)AMINO -1-BENZYL-2-HYDROXYPROPYL CARBAMAT ALS RETROVIRUSPROTEASEHEMMERenHEXAHYDROFURO¬2,3-B FURAN-3-YL-N- 3-¬(1,3-BENZODIOXOL-5-YLSULFONYL)(ISOBUTYL)AMINO -1-BENZYL-2-HYDROXYPROPYL CARBAMATE AS RETROVIRAL PROTEASE INHIBITORfrHEXAHYDROFURO'2,3-B! FURAN-3-YL-N- 3'(1,3-BENZODIOXOL-5-YLSULFONYL) (ISOBUTYL) AMINO! -1-BENZYL-2-HYDROXYPROPYL CARBAMATE EN TANT QU'INHIBITEUR DE PROTEASE RETROVIRALEWO-A-94/05639WO-A-95/06030WO-A-96/33184WO-A-99/67254WO-A-99/67417A. K. GHOSH ET AL.: "Potent HIV protease inhibitors incorporating high-affinity P2-ligands and (R)-[(hydroxyethyl)amino]sulfonamide isostere" BIOORG. MED. CHEM. LETT., vol. 8, no. 6, 1998, pages 687-690, XP002156428WIGERINCK, Piet, Tom, Bert, PaulBreemsdijk 50B-2350 VosselaarBEWANG, Guangyang19016 Harkness LaneGaihersburg, MD 20879USEISSENSTAT, Michael8110 Claiborne CourtFrederick, MD 21702USERICKSON, John, W.5406 Jefferson Blvd.Frederick, MD 21703USTibotec Pharmaceuticals Ltd.07634840TIP-6-PCT/EPOEastgate VillageEastgate Little Island Co CorkIETHE GOVERNMENT OF THE UNITED STATES OF AMERICA,08518020TIP-6-PCT/EPOrepresented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; National Institutes of Health Office of Technology Transfer 6011 Executive Boulevard Suite 325MD 20852-3804USDaelemans, Frank F.R.00091902Tibotec N.V. General De Wittelaan L11 B3B-2800 MechelenBEATBECHCYDEDKESFIFRGBGRIEITLILUMCNLPTSELT20020506LV20020506SI20020506EP200000991720001006enWO20010252402001041220011520020717200229