(19)

(11)

EP 1 222 260 A1

(12)

(43) Date of publication: 17.07.2002 Bulletin 2002/29 (21) Application number: 00971521.0 (22) Date of filing: 19.10.2000

(51) International Patent Classification (IPC)7: C12N 15/10, C12N 1/21, C12N 15/70, A61K 31/711 (86) International application number: PCT/GB0004/006 (87) International publication number: WO 0129/209 (26.04.2001 Gazette 2001/17)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 21.10.1999 GB 9924973 (71) Applicant: Cobra Therapeutics Limited Keele,Staffordshire ST5 5SP (GB)	(72) Inventors: HANAK, Julian Alexis JohnCobra Therapeutics Ltd. KeeleStaffordshire ST5 5SP (GB) WARD, John, MaximDpt Biochem. & Molecular Biology London WC1E 6BT (GB) (74) Representative: Harrison Goddard Foote  Belgrave HallBelgrave Street Leeds LS2 8DD Leeds LS2 8DD (GB)