(19)

(11)

EP 1 225 887 A2

(12)

(88) Date of publication A3: 14.06.2001 (43) Date of publication: 31.07.2002 Bulletin 2002/31 (21) Application number: 00970995.7 (22) Date of filing: 19.10.2000

(51) International Patent Classification (IPC)7: A61K 31/195, A01N 37/46 (86) International application number: PCT/US0028/922 (87) International publication number: WO 0128/552 (26.04.2001 Gazette 2001/17)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.10.1999 US 421131 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)

(72) Inventors: BIEDERMANN, Kimberly, Ann Cincinnati, OH 45241 (US) KRONHOLM, Kurt, Glen Oxford, OH 45056 (US) BEERSE, Peter, William Morrow, OH 45152 (US) MORGAN, Jeffrey, Michael Springboro, OH 45066 (US) MOBLEY, Michael, Joseph Loveland, OH 45140 (US) (74) Representative: Wilding, Richard Alan et al Procter & Gamble Technical Centers Ltd.Patent DepartmentRusham ParkWhitehall Lane Egham,Surrey TW20 9NW Egham,Surrey TW20 9NW (GB)