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EP 1 225 907 A1

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(43) Date of publication: 31.07.2002 Bulletin 2002/31 (21) Application number: 00972031.9 (22) Date of filing: 05.10.2000

(51) International Patent Classification (IPC)7: A61K 38/08, A61K 38/10, A61K 38/16, A61K 39/295, A61K 39/21, C07K 7/00, C07K 9/00, C07K 14/155 (86) International application number: PCT/US0027/766 (87) International publication number: WO 0124/810 (12.04.2001 Gazette 2001/15)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 05.10.1999 US 412863 (71) Applicant: Epimmune Inc. San Diego, CA 92121 (US)

(72) Inventors: SETTE, Alessandro La Jolla, CA 92037 (US) SIDNEY, John San Diego, CA 92130 (US) SOUTHWOOD, Scott Santee, CA 92071 (US) LIVINGSTON, Brian, D. San Diego, CA 92129 (US) CHESNUT, Robert Cardiff-by-the-Sea, CA 92007 (US) BAKER, Denise, Marie San Diego, CA 92126 (US) CELIS, Esteban Rochester, MN 55902 (US) KUBO, Ralph, T. Carlsbad, CA 92009 (US) GREY, Howard, M. La Jolla, CA 92037 (US) (74) Representative: Cripps, Joanna Elizabeth et al Mewburn EllisYork House23 Kingsway London WC2B 6HP London WC2B 6HP (GB)