(19)

(11)

EP 1 226 274 A2

(12)

(88) Date of publication A3: 30.05.2002 (43) Date of publication: 31.07.2002 Bulletin 2002/31 (21) Application number: 00971573.1 (22) Date of filing: 24.10.2000

(51) International Patent Classification (IPC)7: C12Q 1/68, C12N 5/06 (86) International application number: PCT/GB0004/103 (87) International publication number: WO 0131/058 (03.05.2001 Gazette 2001/18)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 25.10.1999 GB 9925210 (71) Applicant: Reneuron Limited Guildford,Surrey GU2 7AF (GB)	(72) Inventors: PRICE, JackInstitute of Psychiatry London SE5 8AF (GB) UWANOGHO, DafeInstitute of Psychiatry London SE5 8AF (GB) (74) Representative: Jappy, John William Graham  Gill Jennings & Every,Broadgate House,7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)