(19)

(11)

EP 1 226 397 A2

(12)

(88) Date of publication A3: 27.09.2001 (43) Date of publication: 31.07.2002 Bulletin 2002/31 (21) Application number: 00976832.6 (22) Date of filing: 02.11.2000

(51) International Patent Classification (IPC)7: F28D 17/00, C09K 3/18 (86) International application number: PCT/US0030/220 (87) International publication number: WO 0135/511 (17.05.2001 Gazette 2001/20)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR (30) Priority: 05.11.1999 US 163726 P (71) Applicant: Baxter International Inc. Deerfield, IL 60015 (US)	(72) Inventor: STERNBERG, Shmuel Palatine, IL 60067 (US) (74) Representative: Dee, Ian Mark  Eric Potter Clarkson,Park View House,58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)