(19)
(11) EP 1 227 834 A2

(12)

(88) Date of publication A3:
08.11.2001

(43) Date of publication:
07.08.2002 Bulletin 2002/32

(21) Application number: 00977538.8

(22) Date of filing: 10.11.2000
(51) International Patent Classification (IPC)7: A61K 38/48, A61K 39/395, A61K 31/7088, A61K 31/593, A61K 31/203, A61K 38/18, A61K 31/573, A61K 33/14, A61K 33/06, C12Q 1/68, A61P 17/00, A61P 27/00, A61P 25/00
(86) International application number:
PCT/EP0011/251
(87) International publication number:
WO 0134/183 (17.05.2001 Gazette 2001/20)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 10.11.1999 EP 99203752
04.08.2000 EP 00202776

(71) Applicant: Vlaams Interuniversitair Instituut voor Biotechnologie vzw.
9052 Zwijnaarde (BE)

(72) Inventors:
  • DECLERCQ, Wim
    B-8510 Marke (BE)
  • VANDENABEELE, Peter
    B-9040 Sint-Amandsberg (BE)
  • LIPPENS, Saskia
    B-9000 Gent (BE)

   


(54) USE OF CASPASE-14 AND CASPASE-14 MODULATORS TO DIAGNOSE AND/OR TREAT SKIN, EYE AND BRAIN DISORDERS