| (84) |
Designated Contracting States: |
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AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
| (30) |
Priority: |
23.01.2001 EP 01101406
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| (43) |
Date of publication of application: |
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07.08.2002 Bulletin 2002/32 |
| (73) |
Proprietor: Nieswandt, Bernhard, Dr. |
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97246 Eibelstadt (DE) |
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| (72) |
Inventor: |
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- Nieswandt, Bernhard, Dr.
97246 Eibelstadt (DE)
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| (74) |
Representative: Binsack, Beate |
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CSL Behring GmbH
Emil-von-Behring-Straße 76
D-35041 Marburg
D-35041 Marburg (DE) |
| (56) |
References cited: :
WO-A-00/68377
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WO-A-01/00810
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- NIESWANDT BERNHARD ET AL: "Expression and function of the mouse collagen receptor
glycoprotein VI is strictly dependent on its association with the FcRgamma chain."
JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 31, 4 August 2000 (2000-08-04), pages
23998-24002, XP002174650 ISSN: 0021-9258
- SCHULTE VALERIE ET AL: "Evidence for two distinct epitopes within collagen for activation
of murine platelets." JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 1, 5 January
2001 (2001-01-05), pages 364-368, XP002174651 ISSN: 0021-9258
- GIBBINS JONATHAN M ET AL: "Glycoprotein VI is the collagen receptor in platelets which
underlies tyrosine phosphorylation of the Fc receptor gamma-chain" FEBS LETTERS, ELSEVIER
SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 413, no. 2, 1997, pages 255-259, XP002143941
ISSN: 0014-5793
- CLEMETSON JEANNINE M ET AL: "The platelet collagen receptor glycoprotein VI is a member
of the immunoglobulin superfamily closely related to FcalphaR and the natural killer
receptors." JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 41, 8 October 1999 (1999-10-08),
pages 29019-29024, XP002143944 ISSN: 0021-9258
- NIESWANDT BERNHARD ET AL: "Long-term antithrombotic protection by in vivo depletion
of platelet glycoprotein VI in mice." JOURNAL OF EXPERIMENTAL MEDICINE, vol. 193,
no. 4, 19 February 2001 (2001-02-19), pages 459-469, XP002174652 ISSN: 0022-1007
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