(19)

(11)

EP 1 229 897 A2

(12)

(88) Date of publication A3: 17.01.2002 (43) Date of publication: 14.08.2002 Bulletin 2002/33 (21) Application number: 00980502.9 (22) Date of filing: 17.11.2000

(51) International Patent Classification (IPC)7: A61K 7/48, A61K 7/50 (86) International application number: PCT/US0031/679 (87) International publication number: WO 0135/905 (25.05.2001 Gazette 2001/21)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.11.1999 US 442286 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)	(72) Inventors: BEERSE, Peter, William Morrow, OH 45152 (US) SMITH, Edward, Dewey, III Mason, OH 45040 (US) (74) Representative: Wilding, Richard Alan et al Procter & Gamble Technical Centers Ltd.Patent DepartmentRusham ParkWhitehall Lane Egham,Surrey TW20 9NW Egham,Surrey TW20 9NW (GB)