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EP 1 229 926 A1

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(43) Date of publication: 14.08.2002 Bulletin 2002/33 (21) Application number: 00980184.6 (22) Date of filing: 15.11.2000

(51) International Patent Classification (IPC)7: A61K 38/06, A61K 38/05, A61K 31/198 (86) International application number: PCT/SE0002/241 (87) International publication number: WO 0135/983 (25.05.2001 Gazette 2001/21)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 16.11.1999 SE 9904132 (71) Applicant: Karolinska Innovations AB 171 77 Stockholm (SE)	(72) Inventors: BURMAN, Lars, G. S-116 65 Stockholm (SE) KARLSSON, Sture S-191 41 Sollentuna (SE) KERLUND, Thomas S-753 30 Uppsala (SE) (74) Representative: Onn, Thorsten et al Stockholms Patentbyra Zacco ABBox 23101 104 35 Stockholm 104 35 Stockholm (SE)