(19)
(11) EP 1 230 264 A1

(12)

(43) Date of publication:
14.08.2002 Bulletin 2002/33

(21) Application number: 00975359.1

(22) Date of filing: 25.10.2000
(51) International Patent Classification (IPC)7C07K 14/435, C07K 14/52
(86) International application number:
PCT/US0029/351
(87) International publication number:
WO 0130/828 (03.05.2001 Gazette 2001/18)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 25.10.1999 US 161400 P

(71) Applicant: HUMAN GENOME SCIENCES, INC.
Rockville, MD 20850-3338 (US)

(72) Inventors:
  • GRZEGORZEWSKI, Krzysztof, J.
    Montgomery Village, MD 20879 (US)
  • SALCEDO, Theodora, W.
    Gaithersburg, MD 20886 (US)
  • KREIDER, Brent, L.
    Bedford, MA 01730 (US)

(74) Representative: VOSSIUS & PARTNER 
Postfach 86 07 67
81634 München
81634 München (DE)

   


(54) THERAPEUTIC COMPOSITIONS AND METHODS FOR TREATING DISEASE STATES WITH MUTANT FORMS OF MYELOID PROGENITOR INHIBITORY FACTOR-2 (MPIF-2)