(19)

(11)

EP 1 232 172 A1

(12)

(43) Date of publication: 21.08.2002 Bulletin 2002/34 (21) Application number: 00980179.6 (22) Date of filing: 14.11.2000

(51) International Patent Classification (IPC)7: C07H 19/04, A61K 31/7064, A61P 7/02 (86) International application number: PCT/SE0002/230 (87) International publication number: WO 0103/6438 (25.05.2001 Gazette 2001/21)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 15.11.1999 SE 9904128 (71) Applicant: AstraZeneca AB 151 85 Södertälje (SE)	(72) Inventors: HARDERN, David,AstraZeneca R & D Charnwood Loughborough,Leics. LE11 5RH (GB) INGALL, Anthony,AstraZeneca R & D Charnwood Loughborough,Leics. LE11 5RH (GB) WILLIS, Paul,AstraZeneca R & D Charnwood Loughborough,Leics. LE11 5RH (GB)