(19)
(11) EP 1 233 765 A1

(12)

(43) Date of publication:
28.08.2002 Bulletin 2002/35

(21) Application number: 00968629.6

(22) Date of filing: 03.10.2000
(51) International Patent Classification (IPC)7A61K 31/00, A61K 31/352, A61K 39/395, A61P 11/06, A61P 37/08, C12N 15/11, A61K 31/7088
(86) International application number:
PCT/US0027/277
(87) International publication number:
WO 0102/8543 (26.04.2001 Gazette 2001/17)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 15.10.1999 US 159872 P

(71) Applicants:
  • MAYO FOUNDATION FOR MEDICALEDUCATION AND RESEARCH
    Rochester, MN 55905 (US)
  • REGENTS OF THE UNIVERSITY OF MINNESOTA
    Minneapolis,Minnesota 55455-2070 (US)

(72) Inventors:
  • GLEICH, Gerald, J.
    Salt Lake City, Utah 84124-4029 (US)
  • BANKERS-FULBRIGHT, Jennifer, L.
    Rochester, MN 55901 (US)
  • O'GRADY, Scott
    White Bear Lake, MN 55110 (US)

(74) Representative: Beresford, Keith Denis Lewis et al
BERESFORD & Co.2-5 Warwick Court,High Holborn
London WC1R 5DH
London WC1R 5DH (GB)

   


(54) TREATMENT OF EOSINOPHIL ASSOCIATED PATHOLOGIES BY MODULATING PKC-$g(d) ACTIVITY