(19)
(11) EP 1 233 965 A1

(12)

(43) Date of publication:
28.08.2002 Bulletin 2002/35

(21) Application number: 00971422.1

(22) Date of filing: 03.11.2000
(51) International Patent Classification (IPC)7C07D 487/04, A61K 31/4725, A61K 31/517, A61P 25/00
// (C07D487/04, 241:00), C07D209:00
(86) International application number:
PCT/EP0010/907
(87) International publication number:
WO 0103/2659 (10.05.2001 Gazette 2001/19)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 05.11.1999 GB 9926303

(71) Applicant: SMITHKLINE BEECHAM PLC
Brentford,Middlesex TW8 9GS (GB)

(72) Inventors:
  • GASTER, Laramie MaryGlaxoSmithKline Pharmaceut.
    HarlowEssex CM19 5AW (GB)
  • HEIGHTMAN, Thomas DanielSmithKline Beecham Pharm.
    HarlowEssex CM19 5AW (GB)

(74) Representative: Giddings, Peter John et al
GlaxoSmithklineCorporate Intellectual Property (CN9.25.1)980 Great West Road
Brentford,Middlesex TW8 9GS
Brentford,Middlesex TW8 9GS (GB)

   


(54) ISOQUINOLINE AND QUINAZOLINE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS