(19)

(11)

EP 1 234 040 A2

(12)

(88) Date of publication A3: 10.01.2002 (43) Date of publication: 28.08.2002 Bulletin 2002/35 (21) Application number: 00987273.0 (22) Date of filing: 20.11.2000

(51) International Patent Classification (IPC)7: C12N 15/36, C07K 14/02, C12Q 1/68, A61K 39/29, G01N 33/569, A61P 31/20 (86) International application number: PCT/EP0011/526 (87) International publication number: WO 0104/0279 (07.06.2001 Gazette 2001/23)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 03.12.1999 EP 99870252 07.12.1999 US 169287 P (71) Applicant: INNOGENETICS N.V. 9052 Gent (BE)	(72) Inventors: STUYVER, Lieven B-9552 Herzele (BE) VAN GEYT, Caroline B-9000 Ghent (BE) DE GENDT, Sija B-9070 Heusden (BE)