(19)

(11)

EP 1 234 058 A2

(12)

(88) Date of publication A3: 25.04.2002 (43) Date of publication: 28.08.2002 Bulletin 2002/35 (21) Application number: 00980700.9 (22) Date of filing: 27.11.2000

(51) International Patent Classification (IPC)7: C12Q 1/68 (86) International application number: PCT/US0032/131 (87) International publication number: WO 0103/8580 (31.05.2001 Gazette 2001/22)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 26.11.1999 US 449402 (71) Applicant: Curagen Corporation New Haven, CT 06511 (US)	(72) Inventors: ROTHBERG, Jonathan, M. Guilford, CT 06437 (US) BADER, Joel, S. F-75116 Paris (FR) (74) Representative: Schlich, George William et al Mathys & Squire100 Gray's Inn Road London WC1X 8AL London WC1X 8AL (GB)