(19)
(11) EP 1 235 568 A2

(12)

(88) Date of publication A3:
18.04.2002

(43) Date of publication:
04.09.2002 Bulletin 2002/36

(21) Application number: 00977179.1

(22) Date of filing: 13.11.2000
(51) International Patent Classification (IPC)7A61K 31/365
(86) International application number:
PCT/US0031/068
(87) International publication number:
WO 0103/4202 (17.05.2001 Gazette 2001/20)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 12.11.1999 US 164749 P

(71) Applicant: The Johns Hopkins UNiversity School of Medicine
Baltimore, MD 21202 (US)

(72) Inventors:
  • PIZER, Ellen, S.
    Clarksville, MD 21029 (US)
  • TOWNSEND, Craig, A.
    Baltimore, MD 21212 (US)
  • KUHAJDA, Francis, P.
    Lutherville, MD 21209 (US)

(74) Representative: Tombling, Adrian George et al
Withers & RogersGoldings House2 Hays Lane
London SE1 2HW
London SE1 2HW (GB)

   


(54) DEPLETION OF CELLULAR COENZYME-A LEVELS AS A MEANS TO SELECTIVELY KILL CANCER CELLS