(19)

(11)

EP 1 235 618 A2

(12)

(88) Date of publication A3: 11.07.2002 (43) Date of publication: 04.09.2002 Bulletin 2002/36 (21) Application number: 00962766.2 (22) Date of filing: 07.09.2000

(51) International Patent Classification (IPC)7: A61P 35/00, A61K 47/48, A61K 31/495, A61K 31/498, A61K 31/401, A61K 31/192, A61K 31/522, A61K 31/138, A61K 31/198, A61K 31/4468, A61P 11/06, A61P 37/08, A61P 5/16, A61P 9/10, A61P 9/12, A61P 9/06, A61P 25/24, A61P 11/08, A61P 29/00, A61P 5/14 (86) International application number: PCT/IB0001/429 (87) International publication number: WO 0101/7568 (15.03.2001 Gazette 2001/11)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 07.09.1999 US 152681 P (71) Applicant: Conjuchem, Inc. Montréal,Québec H2X 3Y8 (CA)	(72) Inventors: EZRIN, Alan, M. Moraga, CA 94556 (US) FLESER, Angelica Montreal, Quebec H1H 4L1 (CA) ROBITAILLE, Martin Terrasse-Vaudreuil, Quebec J7V 5S1 (CA) MILNER, Peter, G. Los Altos Hills, CA 94022 (US) BRIDON, Dominique, P. Ville-Mont-Royal, Quebec H3P 2S2 (CA) (74) Representative: Holmberg, Martin  Bergenstrahle & Lindvall ABP.O. Box 17704 118 93 Stockholm 118 93 Stockholm (SE)