(19)

(11)

EP 1 235 920 A2

(12)

(88) Date of publication A3: 10.01.2002 (43) Date of publication: 04.09.2002 Bulletin 2002/36 (21) Application number: 00982149.7 (22) Date of filing: 20.11.2000

(51) International Patent Classification (IPC)7: C12N 15/82, C12N 15/29, C07K 14/415 (86) International application number: PCT/US0031/657 (87) International publication number: WO 0103/6621 (25.05.2001 Gazette 2001/21)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 19.11.1999 US 167255 P (71) Applicant: Alabama A & M University Normal, AL 35762 (US)	(72) Inventors: DODO, Hortense, W. Huntsville, AL 35816 (US) ARNTZEN, Charles, J. Ithaca, NY 14850-1447 (US) KONAN, Koffi, N'da Huntsville, AL 35816 (US) VIQUEZ, Olga, M. Huntsville, AL 35816 (US) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)