(19)

(11)

EP 1 238 269 A2

(12)

(88) Date of publication A3: 27.12.2001 (43) Date of publication: 11.09.2002 Bulletin 2002/37 (21) Application number: 00985509.9 (22) Date of filing: 08.12.2000

(51) International Patent Classification (IPC)7: G01N 27/403 (86) International application number: PCT/GB0004/711 (87) International publication number: WO 0104/2774 (14.06.2001 Gazette 2001/24)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR (30) Priority: 08.12.1999 GB 9929069 (71) Applicant: IMPERIAL COLLEGE OF SCIENCE,TECHNOLOGY & MEDICINE London SW7 2AZ (GB)	(72) Inventors: MANZ, Andreas East Molesey,Surrey KT8 0JT (GB) TANTRA, Ratna South Kensington,London SW7 2AY (GB) (74) Representative: Robinson, Nigel Alexander Julian et al D. Young & Co.,21 New Fetter Lane London EC4A 1DA London EC4A 1DA (GB)