(19)
(11) EP 1 239 848 A2

(12)

(88) Date of publication A3:
25.07.2002

(43) Date of publication:
18.09.2002 Bulletin 2002/38

(21) Application number: 00974705.6

(22) Date of filing: 01.09.2000
(51) International Patent Classification (IPC)7: A61K 31/00, A61P 3/06, A61P 9/00, C12N 15/12, C12Q 1/68
(86) International application number:
PCT/IB0001/492
(87) International publication number:
WO 0101/5676 (08.03.2001 Gazette 2001/10)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 01.09.1999 US 151977 P
15.03.2000 US 526193
23.06.2000 US 213958 P

(71) Applicants:
  • University of British Columbia
    Vancouver,British Columbia V6T 1Z4 (CA)
  • Xenon Genetics Inc.
    Vancouver,British Columbia V6T 1Z3 (CA)

(72) Inventors:
  • HAYDEN, Michael, R.
    Vancouver, British Columbia V6R 1W9 (CA)
  • BROOKS-WILSON, Angela, R.
    Richmond, British Columbia V7C 4B2 (CA)
  • PIMSTONE, Simon, N.
    Vancouver, British Columbia V6T 1C5 (CA)
  • CLEE, Susanne, M.
    North Vancouver, British Columbia V7N 1M (CA)

(74) Representative: LOUIS, PÖHLAU, LOHRENTZ & SEGETH 
Postfach 3055
90014 Nürnberg
90014 Nürnberg (DE)

   


(54) COMPOSITIONS AND METHODS FOR MODULATING HDL CHOLESTEROL AND TRIGLYCERIDE LEVELS