(19)
(11) EP 1 239 922 A2

(12)

(88) Date of publication A3:
18.10.2001

(43) Date of publication:
18.09.2002 Bulletin 2002/38

(21) Application number: 00972703.3

(22) Date of filing: 09.10.2000
(51) International Patent Classification (IPC)7A61P 19/02, A61P 19/10, A61K 45/00, G01N 33/566
(86) International application number:
PCT/EP0009/883
(87) International publication number:
WO 0102/6737 (19.04.2001 Gazette 2001/16)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 11.10.1999 GB 9924057

(71) Applicants:
  • Novartis AG
    4056 Basel (CH)

    BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE 
  • Novartis-Erfindungen Verwaltungsgesellschaft m.b.H.
    1230 Wien (AT)

    AT 

(72) Inventors:
  • MEYER, Thomas
    60327 Frankfurt (DE)
  • KNEISSEL, Michaela
    CH-4056 Basel (CH)
  • FOURNIER, Brigitte
    F-68400 Riedisheim (FR)

(74) Representative: Becker, Konrad et al
Novartis AGPatent- und Markenabteilung CHLichtstrasse 35
4002 Basel
4002 Basel (CH)

   


(54) TREATMENT OF EXCESSIVE BONE OR CARTILAGE LOSS WITH AN ACTIVATOR OF ROR ALPHA AND ASSAY FOR IDENTIFYING SUCH ACTIVATOR