(19)
(11) EP 1 240 321 A2

(12)

(88) Date of publication A3:
07.03.2002

(43) Date of publication:
18.09.2002 Bulletin 2002/38

(21) Application number: 00984747.6

(22) Date of filing: 21.12.2000
(51) International Patent Classification (IPC)7C12N 15/11, A61K 31/7088, C07K 14/47, A61K 48/00
// A61P13/12, A61P43/00
(86) International application number:
PCT/CA0001/545
(87) International publication number:
WO 0104/6405 (28.06.2001 Gazette 2001/26)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 22.12.1999 US 171443 P
24.07.2000 US 220161 P

(71) Applicants:
  • McGILL UNIVERSITY
    Montreal,Québéc H3A 2T5 (CA)
  • University of Otago
    Dunedin (NZ)

(72) Inventors:
  • GOODYER, Paul
    Montreal West, Québec H4X 1V8 (CA)
  • ECCLES, Roger, Michael
    9015 Mosgid (NZ)
  • TORBAN, Elena
    Brossard, Québec J4X 1L7 (CA)

(74) Representative: Guerre, Dominique et al
Cabinet Germain et Maureau,12, rue Boileau,BP 6153
69466 Lyon Cedex 06
69466 Lyon Cedex 06 (FR)

   


(54) MODULATION OF i PAX /i -2 FOR CONTROLLED APOPTOSIS OR SURVIVAL OF CELLS