(19)
(11) EP 1 242 079 A1

(12)

(43) Date of publication:
25.09.2002 Bulletin 2002/39

(21) Application number: 00966806.2

(22) Date of filing: 22.09.2000
(51) International Patent Classification (IPC)7: A61K 31/44
(86) International application number:
PCT/US0026/056
(87) International publication number:
WO 0102/1176 (29.03.2001 Gazette 2001/13)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 22.09.1999 GR 99100318
23.09.1999 GR 99100321
23.09.1999 ES 9902113
23.09.1999 ES 9902112
23.09.1999 ES 9902111
23.09.1999 ES 9902114
24.09.1999 AR 9904837
24.09.1999 IT MI991997
24.09.1999 JP 30975499
24.09.1999 JP 30975699
24.09.1999 JP 30975599
24.09.1999 DE 19945885

(71) Applicants:
  • Smithkline Beecham
    Philadelphia, PA 19103 (US)
  • SMITHKLINE BEECHAM PLC
    Brentford,Middlesex TW8 9BD (GB)

(72) Inventors:
  • ALCALA, Luis
    28007 Madrid (ES)
  • ANTONNAIDOU, Anastasia
    151 26 Maroussi,Attikis (GR)
  • ATHANASIOU, Kalomira
    151 26 Maroussi,Attikis (GR)
  • BOUROUSI, Maria
    151 26 Maroussi,Attikis (GR)
  • BOUZA, Emilio
    28007 Madrid (ES)
  • BYGATE, Elizabeth
    Harlow,Essex CM19 5AW (GB)
  • CABRIA, Froilan
    28040 Madrid (ES)
  • CERCENADO, Emilia
    28007 Madrid (ES)
  • DEBBIA, Eugenio
    16132 Genova (IT)
  • DEL SOL DIAZ, Maria
    28007 Madrid (ES)
  • DOLCINO, Marzia
    16132 Genova (IT)
  • ESTABAN, Jaime
    28040 Madrid (ES)
  • FAIRLESS, Amanda J.
    Harlow,Essex CM19 5AW (GB)
  • FERNANDEZ-ROBLAS, Ricardo
    28040 Madrid (ES)
  • FINLAY, Jane
    Collegeville, PA 19426 (US)
  • FURUYA, Nobihoko
    Otaku,Tokyo 143 (JP)
  • GARROTE, Fernando Garcia
    28007 Madrid (ES)
  • GIAMARELLOU, Helen
    151 26 Maroussi,Attikis (GR)
  • GIANNAKOU, Paraskevi
    151 26 Maroussi,Attikis (GR)
  • GONZALES-ABAD, Maria Jose
    28007 Madrid (ES)
  • GREKA, Panayota
    115 27 Athens (GR)
  • HAMMER, Heiko
    94315 Straubing (DE)
  • INOUE, Matsushita
    Kanagawa 228-855 (JP)
  • KATO, Kaori
    Gifu 500-8705 (JP)
  • KATSALA, Demetra
    151 26 Maroussi,Attikis (GR)
  • KINZIG-SCHIPPERS, Martina
    90562 Heroldsberg (DE)
  • LOPEZ, Horacio
    3068 Buenos Aires (1425) (AR)
  • LOPEZ, Juan Carlos
    28040 Madrid (ES)
  • MAKINO, Michiko
    Tokyo 143 (JP)
  • MANDARAKA, Aikaterini
    115 27 Athens (GR)
  • MARCHESE, Anna
    16132 Genova (IT)
  • MARIN, Mercedes
    28007 Madrid (ES)
  • MARTINEZ-SANCHEZ, Lucia
    28007 Madrid (ES)
  • MARTIN-PEDROVIEJO, Jesus
    28007 Madrid (ES)
  • MATSUMOTO, Tetsuya
    Tokyo 143 (JP)
  • MIKAELION, Gabriela
    Buenos Aires 1425 (AR)
  • MIYAZAKA, Schuichi
    Tokyo 143 (JP)
  • NABER, Christoph K.
    45122 Essen (DE)
  • NABER, Kurt G.
    94315 Straubing (DE)
  • OGASAWARA, Akira
    Tokyo 143 (JP)
  • OHNO, Akira
    Tokyo 143 (JP)
  • OKAMOTO, Ryoichi
    Kanagawa 228-855 (JP)
  • RUIZ-SERRANO, Maria Jesus
    28007 Madrid (ES)
  • SARACHIAN, Beatriz
    Buenos Aires 1425 (ES)
  • SCARANO, Silvia
    Buenos Aires 1425 (AR)
  • SCHITO, Gian Carlo
    16132 Genova (IT)
  • SORGEL, FritzInstitute for Biomed. Pharmaceutical
    90562 Heroldsberg (DE)
  • SORIANO, FransicoUniversity of Autonoma
    28040 Madrid (ES)
  • Souli, Maria
    151 26 Maroussi, Attikis (GR)

(74) Representative: Waters, David Martin, Dr. et al
GlaxoSmithKlineCorporate Intellectual Property (CN9.25.1)980 Great West Road
Brentford, Middlesex TW8 9GS
Brentford, Middlesex TW8 9GS (GB)

   


(54) METHODS OF USE OF FLUOROQUINOLONE COMPOUNDS AGAINTS BACTERIA