(19)

(11)

EP 1 242 398 A2

(12)

(88) Date of publication A3: 07.03.2002 (43) Date of publication: 25.09.2002 Bulletin 2002/39 (21) Application number: 00988532.8 (22) Date of filing: 20.12.2000

(51) International Patent Classification (IPC)7: C07D 295/02, C07D 295/06, C07D 295/18, C07D 211/58, C07D 211/32, A61K 31/445, A61K 31/495, A61P 9/00, A61P 25/00, G01N 33/50, G01N 33/53 (86) International application number: PCT/CA0001/558 (87) International publication number: WO 0104/6166 (28.06.2001 Gazette 2001/26)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 20.12.1999 US 172765 P 30.12.1999 US 476929 (71) Applicant: Neuromed Technologies, Inc. Vancouver,British Columbia V6T 1Z4 (CA)	(72) Inventor: SNUTCH, Terrance, P. Vancouver, British Columbia V6S 1M1 (CA) (74) Representative: Fisher, Adrian John et al CARPMAELS & RANSFORD43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)