POLYNUCLEOTIDE VACCINES EXPRESSING CODON OPTIMIZED HIV-1 NEF AND MODIFIED HIV-1 NEF - Patent 1242441

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EP 1 242 441 A2

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(88)	Date of publication A3:
	21.02.2002

(43)	Date of publication:
	25.09.2002 Bulletin 2002/39

(21)	Application number: 00989282.9

(22)	Date of filing: 15.12.2000

(51)	International Patent Classification (IPC)⁷: C07H 21/04, C12N 15/00, A61K 39/00

(86)	International application number:
	PCT/US0034/162

(87)	International publication number:
	WO 0104/3693 (21.06.2001 Gazette 2001/25)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

17.12.1999 US 172442 P

(71)	Applicant: Merck & Co., Inc.
	Rahway,New Jersey 07065-0907 (US)

(72)	Inventors:
	SHIVER, John, W. Rahway, NJ 07065-0907 (US) LIANG, Xiaoping Rahway, NJ 07065-0907 (US) FU, Tong-Ming Rahway, NJ 07065-0907 (US)

(74)	Representative: Thompson, John Dr. et al
	Merck & Co., Inc.European Patent DepartmentTerlings ParkEastwick Road Harlow, Essex CM20 2QR Harlow, Essex CM20 2QR (GB)

(54)	POLYNUCLEOTIDE VACCINES EXPRESSING CODON OPTIMIZED HIV-1 NEF AND MODIFIED HIV-1 NEF