(19)
(11) EP 1 242 451 A2

(12)

(88) Date of publication A3:
07.02.2002

(43) Date of publication:
25.09.2002 Bulletin 2002/39

(21) Application number: 00990940.9

(22) Date of filing: 15.12.2000
(51) International Patent Classification (IPC)7C07K 14/52, C07K 14/475, A61K 38/18, A61K 38/19
(86) International application number:
PCT/US0034/039
(87) International publication number:
WO 0104/4294 (21.06.2001 Gazette 2001/25)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 15.12.1999 US 171007 P
31.03.2000 US 193566 P

(71) Applicant: EntreMed, Inc.
Rockville, MD 20850 (US)

(72) Inventors:
  • LIANG, Hong
    Gaithersburg, MD 20850 (US)
  • SIM, Kim, Lee
    Gaithersburg, MD 20878 (US)
  • DEY, Clara
    Germantown, MD 20874 (US)

(74) Representative: Stevens, Ian Edward 
Eric Potter Clarkson,Park View House,58 The Ropewalk
Nottingham NG1 5DD
Nottingham NG1 5DD (GB)

   


(54) COMPOSITIONS AND METHODS FOR INHIBITING ENDOTHELIAL CELL PROLIFERATION