(19)

(11)

EP 1 244 347 A2

(12)

(88) Date of publication A3: 31.01.2002 (43) Date of publication: 02.10.2002 Bulletin 2002/40 (21) Application number: 00986231.9 (22) Date of filing: 22.11.2000

(51) International Patent Classification (IPC)7: A01H 5/00, C12N 5/14, C12N 15/29, C12N 15/52, C12N 15/82 (86) International application number: PCT/US0032/227 (87) International publication number: WO 0103/8489 (31.05.2001 Gazette 2001/22)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 23.11.1999 US 448215 (71) Applicant: CORNELL RESEARCH FOUNDATION Ithaca, NY 14850 (US)	(72) Inventors: YODER, Olen, C. Ithaca, NY 14850 (US) TURGEON, Barbara, C. Ithaca, NY 14850 (US) LU, Shun-Wen Ithaca, NY 14850 (US) (74) Representative: Miles, John Stephen  Eric Potter Clarkson,Park View House,58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)