(19)

(11)

EP 1 244 686 A1

(12)

(43) Date of publication: 02.10.2002 Bulletin 2002/40 (21) Application number: 00983862.4 (22) Date of filing: 01.12.2000

(51) International Patent Classification (IPC)7: C07H 21/04, C12N 1/21, C12N 15/00, C12P 21/00, C07K 14/495, C07K 16/22, A61K 38/18, A61K 48/00, C12Q 1/68, G01N 33/53 (86) International application number: PCT/US0032/745 (87) International publication number: WO 0104/0251 (07.06.2001 Gazette 2001/23)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 02.12.1999 US 168387 P (71) Applicant: Human Genome Sciences, Inc. Rockville, MD 20850 (US)	(72) Inventor: WEI, Ying-Fei Berkeley, CA 94705 (US) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)