(19)
(11) EP 1 248 624 A1

(12)

(43) Date of publication:
16.10.2002 Bulletin 2002/42

(21) Application number: 00978843.1

(22) Date of filing: 21.11.2000
(51) International Patent Classification (IPC)7A61K 31/517, C07D 239/80
(86) International application number:
PCT/US0031/908
(87) International publication number:
WO 0103/7837 (31.05.2001 Gazette 2001/22)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 23.11.1999 US 167113 P

(71) Applicant: SmithKline Beecham Corporation
Philadelphia, PA 19103 (US)

(72) Inventors:
  • ADAMS, Jerry, L.
    Wayne, PA 19087 (US)
  • BOWER, Michael, J.
    Audubon, PA 19403 (US)
  • HALL, Ralph, F.
    Villanova, PA 19085 (US)
  • GRISWOLD, Don, E.
    North Wales, PA 19454 (US)
  • UNDERWOOD, David, C.
    Ambler, PA 19002 (US)

(74) Representative: Gladwin, Amanda Rachel et al
GlaxoSmithKline,Corporate Intellectual Property,CN925.1,Great West Road
Brentford,Middlesex TW8 9GS
Brentford,Middlesex TW8 9GS (GB)

   


(54) 3,4-DIHYDRO-(1H)-QUINAZOLIN-2-ONES AND THEIR USE AS CSBP/p38 KINASE INHIBITORS