(19)

(11)

EP 1 250 046 A1

(12)

(43) Date of publication: 23.10.2002 Bulletin 2002/43 (21) Application number: 00906914.7 (22) Date of filing: 13.01.2000

(51) International Patent Classification (IPC)7: A01N 37/00, A01N 31/14, A61K 31/20, A61K 31/08 (86) International application number: PCT/US0000/881 (87) International publication number: WO 0105/0860 (19.07.2001 Gazette 2001/29)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: Medicis Pharmaceutical Scottsdale, AZ 85258 (US)	(72) Inventors: NIGRA, Thomas, P. Easton, MD 21201 (US) GANS, Eugene, H. Westport, CT 06880 (US) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)