(19)
(11) EP 1 250 431 A2

(12)

(88) Date of publication A3:
17.01.2002

(43) Date of publication:
23.10.2002 Bulletin 2002/43

(21) Application number: 01905039.2

(22) Date of filing: 25.01.2001
(51) International Patent Classification (IPC)7C12N 15/12, C12N 15/63, C12N 1/21, C12N 5/10, C07K 14/435
(86) International application number:
PCT/US0102/439
(87) International publication number:
WO 0105/4651 (02.08.2001 Gazette 2001/31)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 25.01.2000 US 177963 P

(71) Applicant: Digital Gene Technologies Inc.
La Jolla, CA 90237 (US)

(72) Inventors:
  • LEONARDI, Amedeo
    I-20154 Milano (IT)
  • SARTANI, Abraham
    I-20020 Arese (IT)
  • GLASS, James, R.
    Cardiff, CA 92007 (US)
  • SUTCLIFFE, J., Gregor
    Cardiff, CA 92007 (US)
  • HASEL, Karl, W.
    Solana Beach, CA 92075 (US)

(74) Representative: Kaiser, Jürgen, Dr.rer.nat.Dipl.-Chem. 
Winter, Brandl, Fürniss, Hübner,Röss, Kaiser, PoltePartnerschaftPatent- und RechtsanwaltskanzleiAlois-Steinecker-Strasse 22
85354 Freising
85354 Freising (DE)

   


(54) MODULATION OF GENE EXPRESSION IN FORMATION OF FATTY ATHEROSCLEROTIC LESIONS