(19)
(11) EP 1 254 113 A1

(12)

(43) Date of publication:
06.11.2002 Bulletin 2002/45

(21) Application number: 01946849.5

(22) Date of filing: 22.01.2001
(51) International Patent Classification (IPC)7: C07D 207/22, C07D 207/34, C07D 401/12, C07D 403/12, C07K 5/00, A61K 31/435, A61K 31/40, A61P 5/50
(86) International application number:
PCT/DK0100/045
(87) International publication number:
WO 0105/5105 (02.08.2001 Gazette 2001/31)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 24.01.2000 DK 200000112
23.06.2000 DK 200000983

(71) Applicant: NOVO NORDISK A/S
2880 Bagsvaerd (DK)

(72) Inventors:
  • KANSTRUP, Anders
    DK-3060 Espergaerde (DK)
  • LUNDBECK, Jane, Marie
    DK-2600 Glostrup (DK)
  • CHRISTIANSEN, Lise, Brown
    DK-2800 Lyngby (DK)

   


(54) N-SUBSTITUTED 2-CYANOPYROLES AND -PYRROLINES WHICH ARE INHIBITORS OF THE ENZYME DPP-IV