(19)

(11)

EP 1 255 545 A2

(12)

(88) Date of publication A3: 02.05.2002 (43) Date of publication: 13.11.2002 Bulletin 2002/46 (21) Application number: 01906663.8 (22) Date of filing: 25.01.2001

(51) International Patent Classification (IPC)7: A61K 31/195, A61K 31/575, A61K 31/23, A61P 9/00 // A61K31:575, A61K31:195 (86) International application number: PCT/US0102/382 (87) International publication number: WO 0105/4686 (02.08.2001 Gazette 2001/31)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 28.01.2000 US 178778 P (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)	(72) Inventors: SARAMA, Robert, Joseph Loveland, OH 45140 (US) NIEHOFF, Raymond, Louis West Chester, OH 45069 (US) (74) Representative: Kremer, Véronique et al Procter & Gamble Service GmbHSulzbacher Strasse 40-50 65824 Schwalbach am Taunus 65824 Schwalbach am Taunus (DE)