(19)

(11)

EP 1 255 848 A2

(12)

(88) Date of publication A3: 12.09.2002 (43) Date of publication: 13.11.2002 Bulletin 2002/46 (21) Application number: 00951042.1 (22) Date of filing: 14.06.2000

(51) International Patent Classification (IPC)7: C12P 21/00 (86) International application number: PCT/US0040/199 (87) International publication number: WO 0007/7236 (21.12.2000 Gazette 2000/51)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: AL LT LV MK RO SI (30) Priority: 15.06.1999 US 139313 P (71) Applicant: Genetrol Biotherapeutics Oakland, CA 94606 (US)	(72) Inventors: LAU, Allan, S. San Francisco, CA 94127 (US) BROWNING, Laura Brentwood, CA 94513 (US) (74) Representative: VOSSIUS & PARTNER  Siebertstrasse 4 81675 München 81675 München (DE)