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(11)

EP 1 257 565 A1

(12)

(43) Date of publication: 20.11.2002 Bulletin 2002/47 (21) Application number: 01902160.9 (22) Date of filing: 01.02.2001

(51) International Patent Classification (IPC)7: C07K 7/06, C07K 7/08, C07K 14/82, C07K 16/32, A61K 38/08, A61K 39/395, A61K 39/44, A61P 35/00 (86) International application number: PCT/AU0100/090 (87) International publication number: WO 0105/7068 (09.08.2001 Gazette 2001/32)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 01.02.2000 AU PQ536900 14.06.2000 US 593870 (71) Applicant: THE AUSTIN RESEARCH INSTITUTE Heidelberg,Victoria 3084 (AU)	(72) Inventors: MCKENZIE, Ian, F., C. West Brunswick, Victoria 3055 (AU) PIETERSZ, Geoff, A. Greensborough, Victoria 3088 (AU) APOSTOLOPOULOUS, Vasso St Albans, Victoria 3021 (AU) (74) Representative: Hucker, Charlotte Jane  Gill Jennings & EveryBroadgate House,7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)