(19)
(11) EP 1 257 828 A2

(12)

(88) Date of publication A3:
28.03.2002

(43) Date of publication:
20.11.2002 Bulletin 2002/47

(21) Application number: 01904299.3

(22) Date of filing: 09.02.2001
(51) International Patent Classification (IPC)7: G01N 33/58, C12Q 1/68, C07D 311/16
(86) International application number:
PCT/IL0100/134
(87) International publication number:
WO 0105/9156 (16.08.2001 Gazette 2001/33)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 10.02.2000 US 181693 P

(71) Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
92182 Jerusalem (IL)

(72) Inventors:
  • BARENHOLZ, Yechezkel
    93707 Jerusalem (IL)
  • HIRSCH-LERNER, Danielle
    93146 Jerusalem (IL)
  • COHEN, Rivka
    96955 Jerusalem (IL)
  • DAGAN, Arie
    92341 Jerusalem (IL)
  • GATT, Shimon
    92104 Jerusalem (IL)

(74) Representative: VOSSIUS & PARTNER 
Siebertstrasse 4
81675 München
81675 München (DE)

   


(54) DETECTION OF BINDING OF CHARGED SPECIES USING pH- OR POTENTIAL-SENSITIVE PROBES