ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MATRIX METALLOPROTEINASE INHIBITORS - Patent 1259488

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EP 1 259 488 A1

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(43)	Date of publication:
	27.11.2002 Bulletin 2002/48

(21)	Application number: 01912836.2

(22)	Date of filing: 19.02.2001

(51)	International Patent Classification (IPC)⁷: C07D 215/48, C07D 307/85, C07D 209/42, C07D 333/70, C07D 317/68, A61K 31/47, A61K 31/34, A61K 31/40, A61K 31/38, A61K 31/36

(86)	International application number:
	PCT/US0105/349

(87)	International publication number:
	WO 0106/2733 (30.08.2001 Gazette 2001/35)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

25.02.2000 US 513808

(71)	Applicant: Wyeth
	Madison, New Jersey 07940-0874 (US)

(72)	Inventors:
	NELSON, Frances, C. Wyckoff, NJ 07481 (US) ZASK, Arie New York, NY 10128 (US) CHEN, James, M. San Ramon, CA 94583 (US) MOBILIO, Dominick Warren, NJ 07059 (US) NILAKANTAN, Ramaswamy Closter, NJ 07624 (US)

(74)	Representative: Wileman, David Francis Dr.
	Wyeth Pharmaceuticals,Huntercombe Lane South,Taplow Maidenhead,Berkshire SL6 OPH Maidenhead,Berkshire SL6 OPH (GB)

(54)	ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MATRIX METALLOPROTEINASE INHIBITORS