SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEREOF - Patent 1259490

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EP 1 259 490 A2

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(88)	Date of publication A3:
	10.05.2002

(43)	Date of publication:
	27.11.2002 Bulletin 2002/48

(21)	Application number: 01916335.1

(22)	Date of filing: 01.03.2001

(51)	International Patent Classification (IPC)⁷: C07D 225/02, C07D 315/00, A61P 35/00

(86)	International application number:
	PCT/US0106/643

(87)	International publication number:
	WO 0106/4650 (07.09.2001 Gazette 2001/36)

(84)	Designated Contracting States:
	AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
	Designated Extension States:
	AL LT LV MK RO SI

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Priority:

01.03.2000 US 185968 P
30.11.2000 US 250447 P

(71)	Applicant: Sloan Kettering Institute For Cancer Research
	New York, NY 10021 (US)

(72)	Inventors:
	DANISHEFSKY, Samuel, J. Englewood, NJ 07631 (US) LEE, Chul, Bom New York, NY 10021 (US) CHAPPELL, Mark New York-NY10021 (US) STACHEL, Shawn New York, NY 10021 (US) CHOU, Ting-Chao Paramous ,NJ07652 (US)

(74)	Representative: Cornish, Kristina Victoria Joy et al
	Kilburn & Strode,20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)

(54)	SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEREOF