(19)

(11)

EP 1 259 818 A2

(12)

(88) Date of publication A3: 11.04.2002 (43) Date of publication: 27.11.2002 Bulletin 2002/48 (21) Application number: 01905991.4 (22) Date of filing: 23.02.2001

(51) International Patent Classification (IPC)7: G01N 33/68, C07K 16/18, A61P 25/18, C07K 14/47 (86) International application number: PCT/GB0100/783 (87) International publication number: WO 0106/3293 (30.08.2001 Gazette 2001/35)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 24.02.2000 GB 0004415 28.02.2000 US 750395 (71) Applicant: Oxford GlycoSciences (UK) Limited Abingdon,Oxon OX14 4RY (GB)

(72) Inventors: HERATH, M. A. C.,Oxford GlycoSciences (UK) Ltd. AbingdonOxfordshire OX14 4RY (GB) PAREKH, R. B.,Oxford GlycoSciences (UK) Ltd. AbingdonOxfordshire OX14 4RY (GB) ROHLFF, ChristianOxford GlycoSciences (UK) Ltd. AbingdonOxfordshire OX14 4RY (GB) (74) Representative: Blakey, Alison Jane  Oxford Glycosciences (UK) Ltd,The Forum,86 Milton Park Abingdon,Oxfordshire OX14 4RY Abingdon,Oxfordshire OX14 4RY (GB)