(19)
(11) EP 1 261 644 A2

(12)

(88) Date of publication A3:
24.01.2002

(43) Date of publication:
04.12.2002 Bulletin 2002/49

(21) Application number: 01914520.0

(22) Date of filing: 27.02.2001
(51) International Patent Classification (IPC)7: C07K 16/28, A61K 38/17, G01N 33/53, C12N 5/08, C12N 5/10, C12Q 1/68
// C07K1/22, A01K67/027
(86) International application number:
PCT/US0106/178
(87) International publication number:
WO 0106/4750 (07.09.2001 Gazette 2001/36)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 01.03.2000 US 516728

(71) Applicant: Vanderbilt University
Nashville, TN 37212 (US)

(72) Inventors:
  • DANIEL, Thomas, O.
    Nashville, TN 37215 (US)
  • TAKAHASHI, Takamune
    Nashville, TN 37215 (US)
  • MERNAUGH, Raymond
    Frannklin, TN 37069 (US)

(74) Representative: Grünecker, Kinkeldey, Stockmair & SchwanhäusserAnwaltssozietät 
Maximilianstrasse 58
80538 München
80538 München (DE)

   


(54) MODULATION OF THE ACTIVITY OF THE ENDOTHELIAL CELL SURFACE RECEPTOR ECRTP/DEP-1 IN THE REGULATION OF ANGIOGENESIS