(19)
(11) EP 1 263 736 A1

(12)

(43) Date of publication:
11.12.2002 Bulletin 2002/50

(21) Application number: 01909025.7

(22) Date of filing: 08.02.2001
(51) International Patent Classification (IPC)7C07D 235/24, A61K 31/4184, A61P 9/10
(86) International application number:
PCT/US0104/211
(87) International publication number:
WO 0105/8878 (16.08.2001 Gazette 2001/33)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 09.02.2000 US 181234 P

(71) Applicant: THE PROCTER & GAMBLE COMPANY
Cincinnati,Ohio 45202 (US)

(72) Inventors:
  • NIKOLAIDES, Nicholas
    Mason, OH 45040 (US)
  • CHIANELLI, Donatella
    Cincinnati, OH 45241 (US)

(74) Representative: Nargolwalla, Cyra et al
Cabinet Plasseraud84, rue d'Amsterdam
75440 Paris Cedex 09
75440 Paris Cedex 09 (FR)

   


(54) 2-CARBOXAMIDE-BENZIMIDAZOLES USEFUL IN THE TREATMENT AND PREVENTION OF ISCHEMIC REPERFUSION INJURY