(19)

(11)

EP 1 263 737 A1

(12)

(43) Date of publication: 11.12.2002 Bulletin 2002/50 (21) Application number: 01909026.5 (22) Date of filing: 08.02.2001

(51) International Patent Classification (IPC)7: C07D 235/24, A61K 31/4184, A61P 9/10 (86) International application number: PCT/US0104/212 (87) International publication number: WO 0105/8879 (16.08.2001 Gazette 2001/33)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 09.02.2000 US 181236 P (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati,Ohio 45202 (US)	(72) Inventors: NIKOLAIDES, Nicholas Mason, OH 45040 (US) CHIANELLI, Donatella Cincinnati, OH 45241 (US) (74) Representative: Nargolwalla, Cyra et al Cabinet Plasseraud84, rue d'Amsterdam 75440 Paris Cedex 09 75440 Paris Cedex 09 (FR)