(19)
(11) EP 1 263 960 A2

(12)

(88) Date of publication A3:
28.02.2002

(43) Date of publication:
11.12.2002 Bulletin 2002/50

(21) Application number: 01924131.4

(22) Date of filing: 08.03.2001
(51) International Patent Classification (IPC)7C12N 15/13, C12N 15/70, G01N 33/53, G01N 33/68, C07K 16/28, A61K 39/395, C12N 15/62, C12N 1/21, A61P 31/00, A61P 7/00
(86) International application number:
PCT/US0107/501
(87) International publication number:
WO 0107/0984 (27.09.2001 Gazette 2001/39)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 16.03.2000 US 189775 P

(71) Applicant: Genentech, Inc.
South San Francisco, CA 94080-4990 (US)

(72) Inventors:
  • KIRCHHOFER, Daniel, K.
    Los Altos, CA 94024 (US)
  • LOWE, David, G.
    Hillsborough, CA 94010 (US)
  • PRESTA, Leonard, G.
    San Francisco, CA 94109 (US)

(74) Representative: Walton, Seán Malcolm et al
MEWBURN ELLIS,York House,23 Kingsway
London WC2B 6HP
London WC2B 6HP (GB)

   


(54) ANTI-TISSUE FACTOR ANTIBODIES WITH ENHANCED ANTICOAGULANT POTENCY