(19)

(11)

EP 1 265 599 A1

(12)

(43) Date of publication: 18.12.2002 Bulletin 2002/51 (21) Application number: 01914484.9 (22) Date of filing: 23.02.2001

(51) International Patent Classification (IPC)7: A61K 9/20, A61K 9/54, A61K 31/43, A61K 31/545 (86) International application number: PCT/US0105/984 (87) International publication number: WO 0106/2231 (30.08.2001 Gazette 2001/35)

(84) Designated Contracting States: AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR Designated Extension States: AL LT LV MK RO SI (30) Priority: 24.02.2000 US 142582 P (71) Applicant: Advancis Pharmaceutical Corporation Gaithersburg, MD 20878 (US)	(72) Inventor: RUDNIC, Edward, M. North Potomac, MD 20878 (US) (74) Representative: LOUIS, PÖHLAU, LOHRENTZ & SEGETH  Postfach 3055 90014 Nürnberg 90014 Nürnberg (DE)